任职

●哈佛大学医学院附属丹娜-法伯癌症研究院黑色素瘤中心主治医师

●哈佛大学医学院附属布列根和妇女医院皮肤肿瘤主治医师

●哈佛大学医学院讲师

履历

专业领域：黑色素瘤、免疫治疗、靶向治疗

专科医师培训 ：贝斯以色列哈佛医疗中心, 2007 - 2010

住院医师培训 ：贝斯以色列哈佛医疗中心, 2004 - 2007

教育背景 ：塔夫茨大学大学医学院, 2004

荣誉&会员

15年临床经验

美国内科医学委员会，内科肿瘤学, 2010

美国内科医学委员会，内科医学, 2007

专注研究项目-黑色素瘤研究奖, 2007

主题演讲

黑色素瘤和免疫治疗的新进展，视频链接：

http://www.discovercarebelieve.org/connect-with-us/immunotherapy-and-melanoma/

黑色素瘤免疫检查点阻断系列课程，视频链接：

https://hstalks.com/t/3454/immune-checkpoint-blockade-in-melanoma/

会诊案例

49岁、患左上颌窦恶性黑色素瘤的男性向Buchbinder医生寻求关于治疗方案的第二方意见。患者已经接受过手术切除，在会诊前正在接受化疗。Buchbinder医生先认可了患者目前的治疗方案，并为未来的疾病监测推荐了时间规划，还给出了一套备选治疗方案。Buchbinder医生还建议患者进行基因检测，来决定他是否有适用于靶向治疗的特定基因变异。之后，Buchbinder医生还回答了患者关于免疫治疗方法和来美国治疗的问题。这次会诊打消了患者的疑虑，也为他更充分地治疗提供了重要信息。

发表著作

Ott PA, Hu Z, Keskin DB, Shukla SA, Sun J, Bozym DJ, Zhang W, Luoma A, Giobbie Hurder A, Peter L, Chen C, Olive O, Carter TA, Li S, Lieb DJ, Eisenhaure T, Gjini E,Stevens J, Lane WJ, Javeri I, Nellaiappan K, Salazar AM, Daley H, Seaman M, Buchbinder EI, Yoon CH, Harden M, Lennon N, Gabriel S, Rodig SJ, Barouch DH, Aster JC, Getz G,Wucherpfennig K, Neuberg D, Ritz J, Lander ES, Fritsch EF, Hacohen N, Wu CJ.Corrigendum: An immunogenic personal neoantigen vaccine for patients with melanoma.Nature. 2018 03 14; 555(7696):402. View in: PubMed

Sullivan RJ, Infante JR, Janku F, Wong DJL, Sosman JA, Keedy V, Patel MR, Shapiro GI, Mier JW, Tolcher AW, Wang-Gillam A, Sznol M, Flaherty K, Buchbinder E, Carvajal RD, Varghese AM, Lacouture ME, Ribas A, Patel SP, DeCrescenzo GA, Emery CM, Groover AL, Saha S, Varterasian M, Welsch DJ, Hyman DM, Li BT. First-in-Class ERK1/2 Inhibitor Ulixertinib (BVD-523) in Patients with MAPK Mutant Advanced Solid Tumors:Results of a Phase I Dose-Escalation and Expansion Study. Cancer Discov. 2018 Feb; 8(2):184-195. View in: PubMed

Lee H, Hodi FS, Giobbie-Hurder A, Ott PA, Buchbinder EI, Haq R, Tolaney S, BarrosoSousa R, Zhang K, Donahue H, Davis M, Gargano ME, Kelley KM, Carroll RS, Kaiser UB, Min L. Characterization of Thyroid Disorders in Patients Receiving Immune Checkpoint Inhibition Therapy. Cancer Immunol Res. 2017 Dec; 5(12):1133-1140. View in: PubMed

Ott PA, Hu Z, Keskin DB, Shukla SA, Sun J, Bozym DJ, Zhang W, Luoma A, Giobbie Hurder A, Peter L, Chen C, Olive O, Carter TA, Li S, Lieb DJ, Eisenhaure T, Gjini E,Stevens J, Lane WJ, Javeri I, Nellaiappan K, Salazar AM, Daley H, Seaman M, Buchbinder EI, Yoon CH, Harden M, Lennon N, Gabriel S, Rodig SJ, Barouch DH, Aster JC, Getz G,Wucherpfennig K, Neuberg D, Ritz J, Lander ES, Fritsch EF, Hacohen N, Wu CJ. An immunogenic personal neoantigen vaccine for patients with melanoma. Nature. 2017 07 13;547(7662):217-221. View in: PubMed